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Mange Mites - Demodex Treatment
Demodectic Mange treatments
Demodex treatment in
Boxer
Demodex treatment
in Toy Breed - continued
Demodex treatment
in Toy Breed
Demodex mites -
New Treatment?
Mange Treatment
Demodex
- new treatment options
Demodectic mange treatment
Demodicosis treatment
Treatments for Demodicosis
also see Demodex Mange
also see Scarcoptic Mange
Demodectic
Mange Treatments
Question: Hello, my dog, Jake, was diagnosed with Demodectic
mange
about 3 weeks ago. Prior to that diagnosis, I had taken him to the
vet
because I thought he had ringworm. He had a red circular spot
on his
face near his eye that did not seem to be healing. During that
visit, the
vet said that he didn't think that he had ringworm. He said that
he
thought that he had a staph infection and put him on cortisone pills
and antibiotics. Before leaving that day, I told the vet that
I thought
Jake also had an "anxiety licking disorder" because he would lick his
forerms until sores formed. He did not address that issue, however.
I gave Jake the Cortisone and antibiotics as prescribed.
Within 2-3 weeks the red spots had spread
from his face and forearms to the trunk of his body and his hind legs.
I returned to the vet who then did a scraping and said that he had
generalized demodectic mange. He prescribed mytoban and
antibiotics. After reading about demodex I am concerned.
Jakes age is uncertain, he was a sickly stray that I found in
August 2000, who turned into a gorgeous full grown
dog. At the time that I found him, the vet said that he was probably
10-12 weeks. That means that he is now 18 months old and was
about 17
months old when he was put on cortisone. I have now realized
that this
summer, when he would have been about 12 months old, he started with
the red spots on his forearms which I mistook as an anxiety related
disorder. My questions are: 1) Since his first red spots appeared
at
about 1 year, do you think this is juvenile demodex? 2) Do you
think
that the cortisone treatment is what tipped the scales to allow this
disease
to change from localized to generalized? 3) I have insurance
on Jake, and
though I don't like high vet bills, am willing to spend whatever it
takes to make him well. What is your very best treatment advice?
Thanks, Suzanne
Answer: Suzanne-
There are three treatments for demodectic mange that work for most dogs.
The first is the use of amitraz pour on (Mitaban Rx) every other
week
for 6 to 8 applications or until 2 consecutive skin scrapings are negative,
which probably cures demodectic mange in about 80% of dogs when
application directions are followed, although this is just a guess
based on
averaging results from available studies. This is the only approved
treatment for
demodecosis. The second treatment is ivermectin given by injection
or
orally at the rate of 250ug/kg or higher (up to 600ug/kg in resistant
cases) daily until two skin scrapings are negative, which probably
also
works about 80% of the time. This treatment has to be used very
carefully in collies and shelties, who are more likely to suffer toxic
reactions
to ivermectin. The third treatment that is sometimes used is oral
milbemycin (Interceptor Rx) given daily for six to eight weeks and
my best guess is
that it is about as effective as the other therapies. It is probably
wise to be cautious about using this therapy in collies and shelties,
too --
although we have done this on a couple of occasions without problems,
so
far.
Even though we use six to eight weeks as sort of a minimum therapy time,
it is important to remember that it can take up to a year of therapy
in
some dogs to cure demodecosis. It might be possible to cure more dogs
if
intense treatment was used longer than a year but we haven't tried
that.
Some dogs who do not respond to one therapy will respond to one of the
others, so it is probably possible to cure demodectic mange in about
90%
of dogs. In the remaining dogs it is usually possible to control the
disease even if it can't be eliminated, by use of intermittent therapy.
We have
done once a month amitraz applications when this was necessary, in
most
cases. We have a couple of patients who we use ivermectin intermittently
with (probably average two or three month long treatments a year).
It seems to help a lot to use an antibiotic for secondary bacterial
infections during the first two to three months of therapy for
demodectic mange unless treating an early case in which secondary bacterial
infection hasn't occurred. It is also helpful to use an antibacterial
and
antiseborrheic shampoo to treat secondary skin disease and get rid
of
crusts and exudate on the skin. This is especially important when using
amitraz.
There are a couple of legal problems associated with the therapy for
demodecosis, which hamper therapeutic efforts in some patients. The
first legal hurdle is that it is illegal to use an EPA approved product
in a
manner inconsistent with its labelling and Mitaban (Rx) is EPA approved
rather than FDA approved. So once weekly dips, which seem to work
better, are actually illegal. So is long term intermittent use. The
second legal
problem is that the use of ivermectin and milbemycin for the treatment
of demodecosis is an "off-label" use. This isn't illegal, but when
off-label treatments are used they are supposed to be used after an
approved
treatment fails. So technically, your vet should use amitraz first
and
then the other therapies. This is a problem due to the requirements
for
successful use of amitraz in some dog breeds (see next paragraph).
Amitraz works best on short haired dogs and on dogs whose medium to
long
length hair has been clipped completely in order to allow better
exposure to the amitraz pour on. Longer haired breeds will need to
be clipped
repeatedly until therapy is successful, which can be a long time. It
also works best when all scabs and sores have been cleaned off prior
to
application and when an anti-sebborheic shampoo has been used prior
to
application of the pour on and then the dog at least towel dried.
Finally, it is necessary to sponge or pour amitraz onto the whole surface
of the
skin, affected as well as unaffected areas. If these steps are not
taken, amitraz is much more likely to fail.
Now to get to your specific questions. 1) I think that this is almost
certainly juvenile onset demodecosis. 2) I think it is very likely
that
the use of prednisone or other corticosteroids would cause worsening
of
demodecosis in a patient who had this condition and I think that it
is
likely to have done that in your dog's case. 3) I personally
like the
ivermectin therapy best at the present time, although we usually start
with amitraz to try to stay on the right side of the legal issues.
Be
persistent with therapy. Most of the treatment failures result from
giving up on
treatment before it has a chance to work.
Mike Richards DVM
12/14/2001
Demodex treatment
in Boxer
Question: Dear Dr. Richards, I have a 10 month old male Boxer
named Max. He was
diagonsed with Demodex when he was 6 months old. Max has been dipped
in
Mita-ban for four months, once every two weeks. Max's hair has grown
back
and have really had no more health problems due to his Demodex. However,
on
the 15th of January I was suppose to be dipping him for the last time,
but
when the skin scrape came back, it showed one dead mite on his chin.
My vet
has said to keep dipping Maxc until he finds nothing. He said to stop
now I
could run the chance of having the mites come back and be back to square
one. How do you feel, should I continue to dip or is Max pretty safe.
Answer: Lisa-
I agree with your vet. You should continue the dipping, or use alternative
medications for the demodecosis, until no mites are found on two
consecutive scrapings. We usually scrape after each dipping once we
get
down to just a few mites on skin scrapings. If Max has not had problems
with the dippings up to this time it is unlikely that continuing them
would
cause him any problems.
I'm glad that you have had the success you've had so far. Once in a
while
we find a patient who has to have occasional dipping in order to keep
mites
suppressed, because we simply can't get them to stay away completely.
Most
of these patients have only required once a month or once every other
month
treatments. Hopefully, though, Max will go on and be cured of this
problem.
Mike Richards, DVM
1/23/2001
Demodex
in toy breed treatment- continued
Question: I wrote to you recently about my chihuahua x
toy terrier puppy with demodecis and my vet has now increased the Ivermectin
to 300mcg per kilo given orally every second day and restarted the antibiotics
which seems to have led to a significant improvement. Thank you. My question
today is whether or not there is any way of testing for an underlying immunological
problem and/or whether or not there is any way to boost her immune
system. My vet was going to research whether an antiviral drug like
Interferon to boost T cell production could
be helpful and I wondered whether you are aware of any research in
this area.I would be fairly reluctant to try
this without some good supportive evidence that it can help as I know
that Interferon has a range of unpleasant
side effects. My vet seems to think that there is an increasing likelihood
that my pup's problems may relate to an
underlying immunological problem and seems concerned about the possibility
of neurotoxic problems with really
long term use of Ivermectin.
Thanks, Caroline
Answer: Caroline-
I know of a number of patients treated with ivermectin for very long
durations without any noticeable
problems. Most of these patients are being treated daily with 225 to
300 ug/kg of ivermectin. It may
be possible to avoid some of the adverse effects of amitraz (Mitaban
Rx) by treating with yohimbine
prior to dipping with amitraz but sometimes it is necessary to repeat
the yohimbine to cover the whole
time period when reactions occur. This might be an alternative choice
if the ivermectin does seem to
be causing problems at a later time. It is OK to use amitraz and ivermectin
at the same time but I
know that in your dog's case the amitraz seems to cause significant
sedation so that can be held in
reserve, too.
Humans have a lot of side effects associated with interferon use. Cats
have few reported side effects
from interferon use. I have only seen one study that I can remember
on interferon use in dogs and
there were no side effects noted in that study (it was on keratoconjunctivitis
sicca, an immune
mediated eye problem where tear production is inhibited). So I would
think interferon would be
reasonably safe to try but would have to be a little cautious in that
recommendation until I was more
sure of whether dogs are going to be like people or like cats in regards
to side effects.
There are tests for specific immune deficiencies but there has to be
some degree of suspicion for a
particular problem to make these tests practical because there are
a lot of known immune deficiency
disorders at this time. Before going with this approach, I would really
recommend a complete lab
work up, including a broad blood chemistry panel, total blood cell
evaluation and perhaps X-rays of
the chest and abdomen. If all of this fails to point out a problem
then it might be a good idea to
consider asking about referral to a veterinary immunologist or hematologist
for a review of potential
problems with neutrophil disorders or other immune system problems.
I haven't been too impressed with any of the medications or food additives
that are supposed to
stimulate the immune system, yet. Hopefully an underlying problem
can still be identified and treated.
Mike Richards, DVM
4/10/2000
Demodex
treatment for toy breeds
Question: I am a subscriber living in NZ. I have
a 4 month old Chihahua X English Toy Terrier female puppy who was diagnosed
as having severe generalised Demodecis at 11weeks. She had previously been
found to have Ringworm.She received Griseofulvin for 6 weeks and has been
having weekly injections of Ivomectin. She has also had a total of six
weeks on antibiotics for secondary bacterial skin infections.She had a
good initial response to the Ivomectin, with a brief flare up following
her final vaccination,but over the past two weeks has again developed red
scabby patches and hair loss over her throat and face which seem to be
getting worse and spreading despite continued weekly Ivomecitin injections.In
the time she has been receiving treatment she has only had a few days of
looking completely clear, immediately prior to this last flare up. .
It seems that Ivomec and Ectodex are the only treatments
available here and there is a warning not to use Ectodex on Chihahuas on
the bottle. What would be the dangers of using Ectodex on her? (my vet
doesn't know why Chihahuas are specifically excluded from treatment). Is
it likely that increasing the dose of Ivomec would be helpful? She currently
receives 0.08ml but I'm not sure of the concentration.Any information or
advice would be greatly appreciated
Thank you
Caroline
Answer: Caroline-
Ectodex (Rx) is the brand name for amitraz in some areas of the
world. In the U.S. this product is Mitoban (Rx). Toy breeds are thought
to be more susceptible to central nervous system depression from this medication,
making use of it in these breeds more of a risk.
The most common recommendation for ivermectin use, currently, is to
give it daily, orally, for at least six weeks and longer, if necessary.
There isn't any reason that the dosage couldn't be given by injection but
ivermectin injection stings and dogs get tired of it when given at this
frequency. The minimum effective dose reported in the literature is 225mcg/kg
of body weight once daily. The maximum recommended dosage I have seen is
600mcg/kg of body weight. It is best to start at the lower dose and slowly
increase the dosage, if necessary. This is an unapproved use of ivermectin
in the United States but I think that many dermatologists feel that ivermectin
is safer to use than amitraz and so there is a tendency to use it even
though it is unapproved.
Milbemycin (Interceptor Rx) is also reported to kill Demodex mites but
is usually a third choice in treatment due to cost and lower success rates.
This is an option if you wish to avoid the use of amitraz, though.
If you have to use amitraz it is acceptable to give the dog the antidote
for toxicity, yohimbine, prior to dosing with the amitraz. After all, you
only need the toxic effect for the mites, not the pet. Yohimbine
has a shorter duration of action than amitraz, so if it is necessary to
use yohimbine it may also be necessary to give it more than once.
Administration of antibiotics appropriate for secondary skin infection
during therapy for demodecosis helps a lot, in some patients.
Good luck with this. I can provide references for your vet, if necessary.
Mike Richards, DVM
3/12/2000
Demodex mites
- New treatment?
Question: Have been told Pfizer has a new treatment out for this
problem that may be
less toxic that Mitaban and Ivamectin. Unable to find except
a new
parasitic trtment for cattle/pigs which said it is not for dogs
and can be deadly to
them.
To continue....my dog has now been put on Ivamectin liquid (into it
3
days). Told it will take a couple weeks or more for it to work, if
it does. Her
feet are extremely sensitive, one hind foot so bad she cant stand
to put
it on the ground and sometimes falls over. I asked for some type of
topical
pain med for her feet...told to use an aloe vera cream of some type
(fm hlth
food store). She shivers because she hurts and can hardly walk
out to do her
business very far.
I asked if she shouldn't also be on antibiotic, which seemd to help
her
when she was having mitaban dips and was told no. She had one
negative scraping
after dips, but it has returned with a vengence. She has a problem
with
two of her feet bleeing some.
Xrays showed calc area, radiologist said may be tumor, etc. Was
refrred
to Internal Med Specialist.
An ultrasound by Internal Specialist DVM revealed she had a calcified
gallbladder (tols not unusual for old dog) and some minor calc. of
lungs.
Blood tests were not sent with her records.
She has been on thyroid med since she was about 2 yrs old when she
was
properly diagnosed.
As a pup and young dog she had many skin probs ...told due to
allergies...for which Prednisone was given. Later, I was given
antihistamines to help her
thru allergy season...to which she responded well. Has not had
Pred for
years now.....and allergies seemed to go away.
Does Pfizer have something new for Canine Demodex ? HELP.
I love this dog
and can't stand to see her suffer like this... I know she can
be a normal
happy dog when this problem is taken care of.
2nd half of first msg (if you got it) THANK YOU IN ADVANCE
Answer: C.-
Pfizer has a new medication available, selamectin (Revolution Rx), which
kills sarcoptic mange mites but NOT demodectic mange mites, at least
according to its label. It is fairly closely related to ivermectin,
as the
name of it suggests.
Ivermectin is reasonably safe to use for demodectic mange and some
dermatologists use it as a first choice product for this condition
now,
despite the fact that amitraz (Mitaban Rx) is the only approved medication
for the treatment of demodecosis. We use it in some of our cases and
have
not yet run into a major problem with toxicity.
Whatever you do for the demodex is likely to have be continued long
term.
In older dogs this disease shows up because there is something causing
problems with the dog's immune system. Hyperadrenocorticism, liver
disease
or major stresses such as cancers are possible underlying causes of
the
occurrence of demodectic mange in an older dog. In many cases it simply
isn't possible to eliminate the underlying cause, so the demodecosis
has to
be continually suppressed.
I think antibiotics are good idea when there is significant inflammation
and infection around the feet or other areas affected by demodecosis.
I
honestly think it helps to resolve the demodecosis to get rid of other
infectious agents for awhile. So I'd tend to be in favor or their use.
Ask
your vet about this again.
I don't see any reason not to use pain relief medications, either. It
is
important to be sure that there isn't an existing problem that they
might
worsen (especially liver disease) but even in that case it is usually
possible to use at least one of the available pain relief medications.
Ask
your vet if he or she would like to walk around on feet that look like
your
dog's feet look, without pain relievers. If the answer is "no" then
ask why
it seems reasonable to expect your dog to do that. Your vet might have
a
justifiable concern about pain relief medications but he or she should
at
least be able to tell you exactly what that concern is and it should
be
important enough to offset the obvious discomfort associated with not
using
pain relievers.
It is really important to search for the reason that demodecosis has
suddenly appeared in an older dog. I hope you are able to find and
treat an
underlying cause because that would give your dog the best chance for
recovering from the demodecosis completely, with treatment.
Good luck with this.
Mike Richards, DVM
12/2/99
Mange treatment
Question: Whatever happened to just plain ole sulfur and oil
applications for tx
of mange. All the recommended txs I see on all the web sites
call for
vet visits and expensive drugs.
$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$. Seems the most logical
and
common sense approach is to try least expensive FIRST, then go the
big
bucks route.
B. D
Answer: B.-
I think that you can tell from reading our web site that we will recommend
inexpensive treatments when they are likely to be helpful.
Motor oil is not safe to use on pets. Since that is usually the oil
recommended by home remedy enthusiasts in my area, I am assuming it
is the
one you are referring to, too. It is better now than it was when cars
burned leaded gas but it still can cause gastrointestinal problems.
Lime-sulfer dips will kill Sarcoptes mites but not Demodex mites. Other
sulfer containing products do not appear to work for mange based on
a
fairly large number of cases I see in which they have already been
tried.
They do sometimes help with skin conditions that aren't actually caused
by
mange mites but which get called "mange" because people are not aware
that
this is a description of a specific disease rather than a description
of
the symptoms of hairloss and itchiness associated with the mites.
Demodectic mange will often clear up without any treatment at all, making
almost any treatment appear successful at times. This is why we recommend
not treating this form of mange at all unless it becomes generalized
(affects more than five or six spots on the body). If it does become
generalized, there is no effective home remedy that I am aware of.
Sarcoptic mange is easier to kill, does not require many visits to treat
and there are safe and effective medications available for treatment.
In
this case, a questionable home remedy doesn't make economic sense.
It is
cheaper to use an effective medication before secondary complications
from
the mange sets in.
Michael Richards DVM
12/2/99
Demodectic
mange - new treatment options
Q:Hi,
I've been treating 2 dogs for quite some time that were born with demodectic
mange. These puppies (approx. 3 months old at the time) were
dumped in a
nearby park and my husband and I adopted them and have been treating
them for
this mite. We started in September of 1997, treating them with
a shampoo of
benzoil peroxide and then dipping them with Midoban dip. We did
this every 2
weeks with both animals. We kind of got off of the "routine"
somewhere
around November/December and basically had to start all over.
So again we gave them Mitoban dips every other week, along with some
antibiotics to help clear up secondary skin infections and also an
EFA -
Essential Fatty Acid supplement. Of the two dogs (one of which
is mostly
chow {The Female} - and one of which is chow and shows some german
shepherd {The
Male} - we don't know what else they are mixed with. We were
able to get a
"negative" skin scraping on the Male dog in April and we were able
to get him
neutered. Subsequently, the Female had come into heat just prior
to the
male's neutering. I believe that her coming into heat set her
back as we are
still dipping her and seem to be going through the entire process all
over
again.
My question to you is... Do you know anything about Ivermect
liquid (for
pigs and cows), to be effective in treating demodex mange in dogs?
(by
mouth)
My vet has said something about treating the female with monthly heartworm
medicine on a daily basis. She said that sometimes they can get
the
pharmaceutical companies to donate just out of date medicine and then
the vet
can pass it on to us. Have you heard anything on the use of Heartworm
medicine to treat this same mange? Also, can this disease,
once cured...
come back? I would think that treating them with something internally
would
kill something in the bloodstream better than a "topical" dip which
doesn't
really work that way. Is that a correct assumption?
Any comments or suggestions you have would be greatly appreciated.
Thank you...
Michelle (concerned dog owner)
A: Michelle-
When amitraz (Mitaban Rx) dipping is not effective in controlling
demodecosis there are two alternatives that may help. The first is
administration of ivermectin either orally or by injection in high
dosages.
This use is considered to be experimental for dogs and there have been
a
number of suggested dosages, dosing intervals and durations of admistration
suggested for this medication. Your vet will probably have a dosing
plan he
or she is comfortable with. We have used ivermectin for this purpose
with
good success in several dogs. The other alternative is to give milbemycin
(Interceptor Rx) heartworm preventative on a daily basis at the same
dose as
it is given monthly for heartworm prevention. This is also considered
to be
an experimental use in dogs. I have not tried this due to the cost
of the
tablets but this is also supposed to be helpful in treating demodecosis.
If
you have not shaved the dogs prior to dipping with Mitaban you should
consider doing this. It is supposed to work much better when the dogs
are
shaved prior to use. There are also suggestions for using amitraz in
an
"off-label" manner to increase its effectiveness. Many vets use it
weekly
instead of every other week and in desperate situations veterinarians
will
sometimes dip the dog daily but only cover half of the body with the
dip
each day. We haven't tried this either, but only because we haven't
had to yet.
We try to get owners to let us spay female dogs with this condition
since
they do often get worse when they go into heat and we have not seen
much
worsening of the disease due to surgery. It is possible that surgery
could
induce enough stress to make the Demodex infestation worse but we have
not
had that experience yet. We do not wait for the infection to be cleared
prior to spaying.
Demodecosis can return after an apparent "cure". This normally happens
when
the dog's immune system is compromised later in life due to an illness
or
when chronic use of immunosuppressive medications is necessary for
another
condition. A lot of dogs do not ever have completely negative skin
scrapings
for this mite but can be well managed with monthly dips or sometimes
by
dipping at even longer intervals than this. These dogs are always subject
to
a flare-up of the demodecosis if they are sufficiently stressed.
Good luck managing this situation.
Mike Richards, DVM
Demodectic mange
treatment
Q: Dear Dr. Mike; Our 8 month old female boston
terrier was diagnosed with demodectic mange. Our vet recommended an ointment
named "goodwinol." The puppy has a good appetite and is currently on Pedigree
puppy chow, mixed with canned pedigree food. We noticed the loss of hair
on her left shoulder and on her left paw about 2 months ago. Our Vet said
that two treatments are the ointment, and a more toxic treatment of dipping.
Our vet also said that the dog may outgrow the problem. Is our Vet on track
with the diagnosis and medication? Thanks; Mike & Carol Staples
A: Mike and Carol-The standard treatment for localized
demodectic mange (occurring in less than 5 spots) is to use Goodwinol ointment
on the spots and wait for them to disappear. Personally, I don't think
Goodwinol ointment does much, so I just tell people to wait and see if
the spots disappear and do nothing. Lots of clients aren't comfortable
doing nothing, which is probably why Goodwinol continues to be recommended.
Approximately 80% of dogs with localized demodectic mange will outgrow
the condition. It is important to know if your pup will outgrow this condition
on its own if you intend to breed her. If she does not outgrow it without
medication other than Goodwinol and perhaps antibiotics for secondary infections,
she should not be bred. If she does outgrow it then it is probably not
genetic in origin and it is OK to breed her.
If she does develop generalized demodicosis there is only one approved
treatment, which is amitraz (Mitaban Rx) dipping. This works well between
50 and 80% of the time to control generalized mange. When it doesn't work
there are alternative unapproved treatments. Check our dog index for more
information if you ever need to know more about these treatments.
So, my advice in localized cases of demodecosis is to do nothing and
wait. Goodwinol is not harmful, probably isn't helpful but is definitely
OK if you need something to do while you wait. Most of the time this will
work out OK. If not, there are treatment options.
Mike Richards, DVM
Demodicosis treatment
Q: demodecosis in 2y old pit bull txed with ivomec
1x already and did well but recurred and now back on ivomec, primor any
news on immunoregulin to stim. tcells?
A: salmatt- I do not know of any information that
suggests that Immunoregulin (Rx) is helpful in treatment of demodicosis
but it may be. We have had pretty good luck using amitraz (Mitaban Rx)
for demodecosis and it is currently the only approved treatment. We find
that ivermectin (Ivomec Rx) helps in the control of cases that do not seem
to be "curable" but have not had a case yet in which it seemed to eliminate
the mange entirely. We use it after Mitaban hasn't worked, either, so that
may make our success rate lower than someone who uses ivermectin first.
Mike Richards, DVM
Treatments for
demodicosis
Q: Dear Dr. Mike, My husband and I have a thirteen
month old chocolate lab. When he was about four months old, he was diagnosed
with a generalized case of demodex (he had red, pussy bumps all over his
belly). At that time, we were given a generic Keflex for him to take twice
a day. Also, we were to take him in for a Mitaban dip every two weeks.
We finished his antibiotics and continued his dips for six to eight weeks.
Our vet did a skin scrape and found no mites. He gave us a medicated shampoo
to use if we saw any more red bumps. Well, at the end of March or early
April, the bumps were back on the underside of his neck. There was no puss
this time, just scabs. The shampoo did not help at all. When we took him
back to the vet, we were told that we may have stopped the dips too soon
last time and to give him another round of antibiotics and at least eight
more dips. His condition has cleared considerably since we started the
dips and finished the pills, but every now and then we see a small patch
of hair loss. I'm getting worried that our course of action may not work.
Do you have any suggestions for treatment? Should I just keep up the current
treatment and hope that his immune system will strengthen and beat the
demodex? Will we ever be able to work him at the duck blind or will the
marsh water irritate this condition? I'm getting desperate! Any advice
you could give would be greatly appreciated. Thanks!
A: Jennifer- There are three potential treatments
for demodicosis. The only approved one is the Mitaban (Rx) dip. In some
cases it won't completely clear a mite infestation. We usually either ivermectin
or milbemycin (Interceptor Rx) when Mitaban fails. Ivermectin is given
at high dosages, potentially within the toxic range, for this condition.
Despite this, we have not had a toxicity problem yet and feel that it has
helped some dogs become mite free-- but not all. Milbemycin is given at
the standard heartworm preventative dosage but given daily for 6 to 8 weeks.
This can get pretty expensive and we haven't actually tried it yet so I
don't have much personal experience to offer. We have usually resorted
to using Mitaban and/or ivermectin on a monthly basis to control the Demodex
and let the dog live with it.
I don't see any reason why your dog couldn't hunt while affected with
demodicosis if it is mostly controlled. You might want to ask your vet
about this too. I live very near the Chesapeake Bay and many of my patients
spend a great deal of time in the water. I don't remember any complications
that seemed to be related to this in demodicosis cases.
The other possibility is that the mites are gone but that your dog has
another problem or is simply highly susceptible to staph skin infections.
Many Labs are. In these cases, repeated use of antibiotics may be necessary
but usually the skin disease can at least be controlled. If allergies or
an unrelated immune system problem is present it may be necessary to diagnosis
this and try to control it. Getting control of allergies is harder in a
dog prone to demodicosis since the use of corticosteroids can make return
of the demodicosis a problem. Allergy testing and the use of hyposensitization
should be considered for these dogs.
Mike Richards, DVM
Last edited 08/30/02
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